Gaucher Disease A Rarity in Three Types Essay examples

Gaucher Disease: A Rarity in Three Types Ethnicity can provide individuals with wonderful traditions and celebrations of ones heritage. However, for some Ashkenazi Jews, ethnicity brings them much more than they bargained for: a rare condition causing a wide array of liver, lung, spleen, bone and bone problems. Ethnicity brings them Type I Gaucher Disease. Type II and Type III are the two other forms of this rare genetic condition, and can occur at equal frequencies in all ethnic groups. Gaucher disease was first described in 1882 by Doctor Philippe Charles Ernest Gaucher from France (2) . Type I , the most frequently seen form of the disease, can affect people of multiple ethnic backgrounds. However, its prevalence is greatest†¦show more content†¦(2) . Each of the three types of Gaucher Disease affect many systems of the body. Type I of the disease, which is the most mild form and is most frequently seen, is the only form of Gaucher which does not affect the nervous system. Typically, the average age of onset for Type I Gaucher is 21 years (6) . Approximately 1 in 10 Ashkenazi Jews is heterozygous for type I. Although the condition is non-neuronopathic, patients can exhibit a wide array of symptoms ranging from increased spleen and liver volume, lung compression, a variety of bone problems including lesions, bone tissue death and pain, and anemia and easy bruising. Individuals with Type I Gaucher Disease typically have a life span of 6 to 80 years (5) . Within families, the severity of Type I of the condition varies immensely, thereby making it impossible to determine which family members will suffer from the most severe symptoms. Gaucher Disease is different from most other autosomal recessive conditions in that one of the nonfunc tional glucocerebrosidase genes (which are characteristic of Gaucher Disease) is passed o1n to each of the patients offspring, causing them all to be carriers. Among Ashkenazi Jews, it has been presumed that around 1 in 450 Ashkenazi Jews has two mutated copies of the glucocerebrosidase gene (4) . While Type I Gaucher is by far the most common form of the disease, Type II is excessively rare; among newborns, less than 1 in 100,000 have Type

Business Analysis Verizon Wireless - 1152 Words

Business Analysis Lakecia Brown Strayer University Dr. Brian Collins BUS508: Contemporary Business October 25, 2015 Verizon Wireless Prior to the 21st century, most of the world’s communication was done via telephone or through face-to-face interaction. The advancement of the cell phone, the ease of emailing replaced the standard letter writing or silent immediate communication with texting. The instant access of a camera could capture moments never caught before. No longer did individuals in society have to wait until they arrived home to play video games, they could access their favorites through their phones or tablets. With the beginnings of such companies as US Cellular and Sprint, Verizon Wireless researched the models to analyze successes and failures to devise a business concept that would transcend location and time. Verizon Wireless is one company that is dedicated to â€Å"empowering people with revolutionary technology†. Verizon is considered one of the world’s largest cellular phone providers with the highest customer satisfaction rating. The headquarters i s located in Basking Ridge, NJ and Verizon employs over 85,000 individuals around the world. The employees are considered one of the company’s greatest assets where each individual’s talent is valued. Employees hold positions in the fields of sales, customer service, management, technology and network positions. Verizon makes its company very enticing for employees by providing anShow MoreRelatedVerizon: Analysis of the Wireless Business2408 Words   |  10 PagesVerizon is a major telecommunication provider in the United States. The company is the market leader, with $110 billion revenue and $2.4 billion in profit (MSN Moneycentral, 2012). Verizon has steady revenue streams that are largely based on a subscription model. It has several business segments, including wireless (63.3% of revenues) and wireline (36.7%) (2011 Verizon Annual Report). 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The SWOT analysis showed internal strengths in technology diversification, a large and talented employee resource pool, and an expansive network footprint. Internal weaknesses were revealed that centered on post merger issues such as corporate culture issues, impending workforce retirements, and a lack of systems or process consolidation. External opportunities include the potentialRead MoreMobile, Global, And Virtual Business Environment1027 Words   |  5 Pagestouches as many technology-related business sectors as telecommunications, which, by definition, encompasses not only the traditional areas of local and long-distance telephone service, but also advanced technology-based services including wireless communications, the Internet, fiber-optics and satellites. 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Cook ACC 205: Principles of Accounting I Instructor Thomas Sutton 22 August 2015 Financial Statement Analysis Company Overview Verizon Wireless Communications is a wireless telecommunication company. It was formed in June of 2000 with the merger of Bell Atlantic Corporation and GTE Corporation. It is known as America’s first nationwide 3G wireless broadband network and serves more of the United States population than its competitorsRead MoreComponents Of A Successful Business System1309 Words   |  6 PagesThere is the need to know what a business system is and how to construct useful systems and measures to run a business. A system is a process, technique, or an action intended to accomplish a detailed result.. Establishing a valuable business systems helps attain outcomes that are unfailing, assessable, and eventually do good for customers. Systems and processes are the vital initiative of your company, whether you notice is or not. Every aspect of your business is associated with a system that canRead MoreVerizon Communication Swot Analysis716 Words   |  3 PagesSWOT ANALYSIS INTRODUCTION. A business must analyze their general environment and their industries competitive environment in order for the business to understand their environment. (Dess, Lumpkin, Eisner, McNamara 2014.) This comes by doing a SWOT Analysis which is a basic technique. By doing a SWOT Analysis, the company can identify its strengths and weaknesses which are the internal forces. The analysis also identifies the external forces which are the opportunities and threats in the industry

Increased life expectancy free essay sample

With the rapid development of the economy, people’s life quality has become better. Compared with the past, life expectancy is linear growth now. Take Japan as an example, men are 67.74 years and females are 72.92 years in 1965, but in 1995 average life expectancy of men was 76.57 and for women it was 82.98 years. According to some organizations it is predicted that the growth of the human life expectancy will increase 0.86 years per decade between 2000-2080. This includes male and female life expectancy. However, what causes lead to the life expectancy increasing? In addition to improved quality of life, what other factors play an important role in life expectancy increasing? Obviously, now people are increasingly concerned about their health care issues. So a large number of people keep healthy by doing some exercise. In the morning, many old people are running and swimming. Meanwhile, in order to prevent disease early people go to the hospital for regular physical check-ups. We will write a custom essay sample on Increased life expectancy or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Recently, technology is developing rapidly. Especially the development of medical technology, some diseases can be cured and vaccines of preventable diseases are being invented. For example, vaccines are being made for epidemics and hepatitis. Research reveals that genetics also influence life expectancy. Generally speaking, parents who live long also have children who have live long. German scientists found that after investigating people who are older than 100 years, their parents’ average age was longer than the average population by 9 to 10 years. To sum up, the world health organization has declared that life expectancy increases of everyone is affected by these factors, 70% depending on themselves, 15% depending on genetic factors, and 15% depending on medical conditions. And the important point is doing exercise and keeping an optimistic attitude.